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Many of the proteins produced in our bodies are produced by skeletal muscle. We often only associate skeletal muscle with the locomotion of our bodies, yet the muscular system and its mechanical activity is much more complex. Skeletal muscle in actuality is the largest organ in the body.
Muscle fiber contractions are required for breathing, posture, movement and the application of force and as importantly the secretion of proteins. Through its secretions muscles communicate with the liver, pancreas, bones, adipose tissue, its own cells and even the brain.
Cytokines are a broad range of small proteins that transmit various signals for cell survival, proliferation, differentiation, and functional activity. Those expressed by skeletal muscle are classified as ‘myokines’. Myokines released by muscle fibers exert paracrine (cell producing signals to induce changes in nearby cells), endocrine (cell communication through the circulatory system), and autocrine effects (signaling through hormones or chemicals to the receptors of the same cell).
Many proteins are dependent upon the muscle's contraction. A physically limited lifestyle and excessive sedentary behavior alters myokine response and becomes a cause for many chronic diseases. Many participate in aerobic fitness, flexibility, mobility training, yoga, walking and high intensity movements - which are all constructive components of fitness. Discounting none of the aforementioned activities, one should include weight training throughout their entire lives as the benefits of skeletal muscle retention and its contractions are essential in living a longer healthier lifestyle.
Get and keep Strong.
Releasing Proteins for a Healthy Lifestyle